New research from the University of California, Los Angeles (UCLA) shows that creatine, a compound widely used as a sports supplement, can enhance the activity of dendritic cells, a type of immune cell that helps direct killer T cells to attack tumors.
The study, published in the journal iScience, was conducted in mouse models and human cells and builds on earlier work from the same laboratory demonstrating that creatine powers killer T cells. According to senior author Lili Yang, a professor at UCLA and a member of the Broad Stem Cell Research Center, the findings suggest that creatine may serve as a supplement to support immune responses that modern immunotherapies depend on.
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