Supplements explored: What science says really works for fatigue and what could be dangerous
Fatigue is often linked to specific deficiencies, with iron and B vitamins (like B12) being crucial for oxygen transport and cellular energy. Supplements can help when a deficiency is diagnosed but are not universally recommended.
Creatine aids high-intensity exercise and cognition, protein can reduce low-energy periods and tyrosine may improve short-term cognitive function under stress.
Metabolic regulators like selenium, magnesium and zinc are essential for thyroid function and energy production and correcting imbalances may reduce fatigue, though risks of toxicity exist with over-supplementation.
Herbal and other aids, such as ashwagandha, melatonin and tea (caffeine with L-theanine), show potential for improving energy, mental clarity and sleep quality, but more clinical research is needed for some.
Significant risks exist, especially with energy and performance supplements, which are linked to a three-fold increase in severe medical events for young adults.
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