A new review published in Nutrition Reviews has found that higher consumption of ultra-processed foods (UPFs) is associated with a 32% higher risk of depression and an increased risk of cognitive decline, according to the report. The review analyzed 81 existing meta-analyses and 12 lead publications covering 13 health outcomes, with evidence spanning research published through December 2025.
For every 10% increase in UPF intake, the risk of type 2 diabetes rises by 10%, researchers reported. The strongest evidence, rated as high-certainty, was for type 2 diabetes, while links to cognitive decline and depression were based on moderate- to low-certainty evidence.
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