A pooled analysis of 12 studies involving 497,336 participants across 14 countries found that lower grip strength was associated with higher odds of developing depression over time, according to the study.
The research, published in the Journal of Psychosomatic Research, tracked participants for a combined total of more than 3.4 million person-years, the study stated. All included studies excluded participants who already had depression at baseline, allowing researchers to track new cases rather than existing illness, according to the study. That design element rules out the possibility that depression itself caused people to become less active and therefore weaker, a common pitfall in this type of research.
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