Weaker, more fragmented daily rest-activity rhythms are linked to smaller memory-related brain regions in older adults.
Consistent daily movement patterns, not just exercise intensity, appear to protect brain volume.
The hippocampus, parahippocampus and amygdala—areas vulnerable to Alzheimer’s—show shrinkage with fragmented rhythms.
Older adults with more disrupted rhythms experienced faster ventricle expansion, a marker of brain atrophy.
Breaking up sitting every 30-60 minutes may help maintain brain structure years before cognitive symptoms appear.
The hidden brain cost of sitting between workouts
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