Key Findings: Diet, Weight Loss, Exercise Outperform Metformin
A 21-year study published in JAMA found that adults with prediabetes who followed an intensive lifestyle intervention reduced their risk of developing multiple chronic conditions by 21% compared to those receiving placebo. The lifestyle group, which followed a reduced-calorie, low-fat diet, engaged in at least 150 minutes of physical activity weekly, and achieved 7% weight loss, had a median of 4 chronic conditions at follow-up. In contrast, the metformin and placebo groups each had a median of 5 conditions, according to the report.
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