Study Identifies Muscle Protein NOX4 as Missing Link Between Exercise and Healthy Aging
Researchers at Monash University have identified a muscle protein called NOX4 that declines with age and inactivity, a change they say may be the molecular connection between exercise and healthy aging. The findings, published in the journal Science Advances, suggest that when NOX4 falls, the body loses a key signaling system that triggers protective enzymes, leading to frailty, insulin resistance, and advanced liver disease in animal models.
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