Study: Chronic Stress Ages Immune System via Gut-Brain-Bone Marrow Axis, Mouse Data Shows
Chronic psychological stress in mice drove blood stem cells to behave as if from an older organism, reducing their ability to self-renew and produce infection-fighting immune cells, according to a study published July 2, 2026 in Cell Stem Cell. Researchers at Sun Yat-sen University in Guangzhou, China, traced the damage through a brain-gut-bone marrow pathway, implicating a specific gut bacterium and its metabolite.
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