Researchers at Baylor College of Medicine have found that increasing levels of the protein Sox9 in astrocytes helps clear amyloid plaques and preserve cognitive function in mouse models of Alzheimer’s disease, according to a study published in Nature Neuroscience. [1]
Mice that already showed memory deficits and had amyloid plaques in the brain before the intervention retained better cognitive function over six months when Sox9 was elevated, the researchers reported. [1] The study found that mice with higher Sox9 levels maintained the ability to recognize familiar objects and environments, indicating preserved memory. [1]
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