Introduction
A new study led by Mayo Clinic researchers has mapped a precise biological mechanism explaining how vitamin D supplementation improves symptoms in patients with inflammatory bowel disease (IBD), according to a report published in the journal Cell Reports Medicine. The 48-patient study demonstrates that vitamin D reprograms immune cells, instructing them to stop attacking beneficial gut bacteria, the report stated. This mechanistic explanation offers the clearest view yet of why clinical observations have long linked vitamin D deficiency to worse IBD outcomes, researchers said.
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