Lifestyle Changes Associated with Lower Chronic Disease Risk Than Metformin in 21-Year Prediabetes Study
Adults with prediabetes who received intensive lifestyle coaching were 21% less likely than those in a placebo group to develop two or more chronic diseases over 21 years, according to a JAMA analysis published in 2026. The same participants had a 43% lower risk of developing the most expensive combinations of chronic illness, researchers reported.
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