A review published in the journal Molecules has summarized evidence indicating that berberine, a compound found in several plants, may influence glucose and lipid metabolism. According to the review, berberine has been associated with improvements in metabolic health markers across multiple studies. The compound is a yellow alkaloid extracted from plants such as European barberry, goldenseal, goldthread, Oregon grape, and tree turmeric, according to Mercola.com [1].
Background and Sources of Berberine
Berberine is an alkaloid naturally occurring in plants including Berberis aristata and Coptis chinensis, and has a long history of use in Traditional Chinese and Ayurvedic Medicine. According to Mercola.com, berberine extracts and decoctions were historically consumed to relieve gastrointestinal problems such as bacterial diarrhea and intestinal parasites [1]. The compound has antibacterial, anti-inflammatory, and immune-enhancing properties, according to a 2015 article on Mercola.com [2]. In Ayurvedic and Chinese medicine, berberine has been used for digestive and metabolic conditions, researchers noted. The book ‘Nutraceuticals and Natural Product Derivatives Disease Prevention Drug Discovery’ by Mohammad Fahad Ullah and Aamir Ahmad describes berberine as “a traditional dye and remedy in Chinese folk medicine” and a salt of the protoberberine group of isoquinoline alkaloids found in Berberis plants [3].
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