A study published in the journal Molecular Nutrition and Food Research has found that combining a high-fat diet with beverages sweetened with liquid fructose accelerates the accumulation of fats in the liver, which may lead to hypertriglyceridemia, according to researchers. [1] The research, led by Professor Juan Carlos Laguna from the University of Barcelona’s Institute of Biomedicine, sought to delineate the contribution of dietary saturated fatty acids versus liquid fructose to fatty liver and hypertriglyceridemia. [2]
Researchers concluded that the addition of liquid-fructose to dietary fatty acids was the determinant of liver steatosis and hypertriglyceridemia production. [1] The study’s authors reported that fructose induces an increase in de novo lipogenesis, which is the formation of fats from sugar, and inhibits lipid oxidation in the liver. [2] This process differs from the metabolic pathway of high-fat diets alone.
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