Nearly 100 businesses have left Colorado since 2019, state’s largest business group warns

Colorado has lost 98 companies that have moved out of state since 2019, according to data from the state’s largest business group.The data was compiled as part of a report tracking company relocations by the Colorado Chamber of Commerce’s foundation, which says the report “can be key to understanding Colorado’s risk factors when it comes to economic competitiveness, business growth and corporate attraction.”
In 2025, the state saw 27 relocations or lost opportunities, up from 22 the year prior. 
The foundation also estimated that more than 13,600 known jobs were lost due to the relocations.
“What we hope people take away from this report is not that it’s about any one company, but that it’s a trend and a trend that we should take seriously and address before it gets worse,” said Colorado Chamber Foundation Executive Director Rachel Beck.
Most of the businesses lost since 2019 went to Texas (21) and California (10), according to the report, which gathered data from news reports, U.S. Security and Exchange Commission filings, notices filed with the state, and other sources.
Last year, AGC Biologics, which accounted for 267 jobs, left Colorado for Washington state, while the company True Anomaly (400 jobs) decided to expand to California while still maintaining some presence in Colorado.
According to the chamber foundation’s analysis of SEC filings, the state has gone from having 174 business headquarters in 2022 to 140 in 2025. 
When adjusted for headquarters gained, the state experienced a net loss of six company headquarters last year. Earlier this year, Palantir Technologies, at the time the largest public company in the state, quietly announced it relocated from Colorado to Florida.
While not included in the foundation’s report since it happened in 2026, an analysis by the Common Sense Institute estimated over 700 jobs lost and a $106 million hit to the state’s gross domestic product.
Gov. Jared Polis’s office did not respond to a request for comment.
The chamber foundation said its relocation report is part of a broader strategic plan called “Vision 2033” that seeks to “foster long-term economic growth and resiliency.”
“We want to make sure that we are identifying Colorado’s challenges and opportunities so that we can address them and make sure that this continues to be a great place to do business and a great place to live,” Beck said.
The chamber also maintains a scorecard on the state’s business climate and competitiveness, which it says is hampered by regulatory burdens and high cost of living. 
Colorado is the sixth most regulated state in the U.S., according to another report by the business group.
One bipartisan bill the chamber is supporting is Senate Bill 26-137, which would require state-level department rules to be reviewed at least every five years.
The Senate Appropriations Committee is scheduled to hear the legislation on Friday.

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