Broken sleep, broken gut: New study reveals how sleepless nights sabotage your digestive health
Chronic sleep disruption directly damages the gut by sending distress signals from the brain that cripple intestinal stem cells, impairing the daily repair of the gut lining and increasing the risk of serious digestive diseases.
A specific biological pathway is identified: Faulty signals from a sleep-deprived brain travel down the vagus nerve to the gut, triggering a serotonin surge that causes oxidative stress and halts stem cell function.
This discovery challenges the outdated mechanistic medical model that treats organs in isolation, providing concrete evidence for the integrated gut-brain axis where brain states directly dictate physical gut health.
The research explains the link between modern epidemics, directly connecting widespread sleep deprivation to the rising prevalence of chronic gastrointestinal disorders like inflammatory bowel disease.
It points toward new holistic treatments by identifying molecular targets to intercept harmful brain-gut signals and elevates sleep hygiene to a critical component of preventive medicine.
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