Exercise Linked to Brain Changes That Boost Stamina
Researchers at the University of Pennsylvania found that exercise alters brain activity in a region called the ventromedial hypothalamus, specifically in steroidogenic factor-1 (SF1) neurons. According to a study published May 16, 2026, in the Cell Press journal Neuron, these neurons remain active for at least an hour after exercise and appear to help the body adapt to training. Blocking these neurons prevented mice from gaining endurance even when they exercised normally, the study stated.
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